TO EVALUATE THE VINCA(Catharanthus roseus) LEAVES EXTRACT ON ONCO MICE

MARS-MAHATMA RAKESH SINGH

ABSTRACT: 

Catharanthus roseus, population known as Vinca rosea, In India it is known as 'sada bahar'

a significant medicinal plant from the Apocynaceae family, used to treat 

various life-threatening diseases. It is known by names such as bright 

eyes, cape periwinkle, pink periwinkle, and Madagascar periwinkle. The plant contains chemical compounds like carbohydrates, flavonoids, 

saponins, and alkaloids, including vinblastine, vincristine, vindoline, 

monoterpenes, sesquiterpenes, indole, and indoline glycosides. 

Catharanthus roseus is native to the Indian Ocean Island of Madagascar 

and was once considered an endangered species in the wild. However, it 

is now found in many tropical and subtropical regions worldwide.

The plant demonstrates various 

pharmacological activities, such as anticancer, antidiabetic, antimicrobial, 

antioxidant, memory enhancement, wound healing, hypotensive,  antiulcer, and hypolipidemic effects. In this review article express taxonomy, synonym, vernacular names, distribution, 

ethnomedical uses, phytochemicals and pharmacological activities of Catharanthus roseus.

And to study it's anticancer activity in oncomice.

INTRODUCTION: 

Medicinal plants have been 

used extensively in traditional medicine throughout history. Ethnobotanical knowledge about these plants and their applications by indigenous communities is valuable for preserving cultural heritage, promoting biodiversity, enhancing 

community healthcare, and advancing drug development.

Catharanthus Roseus L. a perennial plant are native of INDIA From southern and northern spread throughout INDIA

The flowers produced by these plants are planted for decorative purposes are of colours such as pink, and the flowers are offered in rituals and prayer of all in temple as well in Home.

purple and white Madagascar periwinkle is used traditionally for number of ailments such as high blood pressure, infection and diabetes mellitus. The stem produces a milky sap that serves as a source 

for over 70 indole alkaloids". Vincristine and vinblastine were isolated from this plant are well known anti-cancer drugs for Hodgkin’s lymphoma and childhood leukemia respectively also used by the sage of variou part of India since 482 A.D., In INDIA for the treatment of breast cancer and testicular cancer.

(PRACHIN AUSHADHI)

(AYURVEDA)

mail, rakeshmahatmasingh@gmail.com

+919428013281

MARS-MAHATMA RAKESH SINGH